Research Activites

List of Publication & Project work done

Pharmaceutics Projects

Sr.No	Dissertation title
01	Formulation studies on drugs going to be off patent to develop pipeline generic solid oral dosage forms.
02	Formulation development studies on microemulsion gels containing herbal excipients as permeation enhancers.
03	Formulation and evaluation of an antineoplastic lyophilized dosage form.
04	Formulation and evaluation of nanosuspension containing anti inflammatory drugs.
05	Formulation and evaluation of a model anti retroviral drug complexed with cyclodextrins.
06	Formulation and evaluation of fast dissolving dosage forms containing dietary supplements.
07	Formulation and evaluation of suspension of coated sustained release phenylephrine hydrochloride microcapsules.
08	Formulation development studies on a multiparticulate drug delivery system for management of cardiovascular disorders.
09	Design and evaluation of advanced drug delivery system.
10	Design and evaluation of controlled release drug delivery system of generic drug.
11	Formulation development studies on a transdermal patch based anti depressant drug delivery system.
12	Formulation and evaluation of a gastroretentive dosage form of a model drug with narrow absorption window.
13	Product development studies on prenteral colloidal delivery system of a drugs of herbal origin.
14	A study on concurrent process validation of dexamethasone phosphate injection.
15	Design, evaluation and optimization of a colon specific targeted drug delivery system.
16	Study of concurrent process validation of flutamide capsule dosage form.
17	Process optimization and trouble shooting of finasteride granulation using single pot fluid bed processor.
18	Studies on a transungual drug delivery system for topical treatment of onychomyeosis.
19	Formulation development studies on a sustained release drug delivery system for management of cardiovascular disorders.
20	Design and evaluation of injectable suspension containing anti inflammatory glucocorticoids.
21	Design and evaluation of colloidal dispersion system of a model bcs class-ii drug.
22	Formulation and evaluation of solid oral dosage forms in site/technical transfer products.
23	Development and evaluation of bio adhesive particulate system for delivery of model anti microbial drug.
24	Design and evaluation of colon specific drug delivery system of methotrexate.
25	Development and evaluation of voglibose tablets.
26	Studies on lyophilization of injectable formulations for improvement of drug stability and shelf life.
27	Development and evaluation of extended release tablet of an anti cholinergic drug.
28	Formulation and evaluation of floating drug delivery system containing ferrous sulphate for the treatment of aneamia
29	Formulation and evaluation of solid oral drug delivery systems for clinical management of aids.
30	Design and evaluation of micro emulsions as a potential delivery system for poorly bioavailable drugs.
31	Formulation and evaluation of gastroretentive drug delivery system containing fluoroquinolone antibiotic.
32	Study on biodegradation of pharmaceutical polymers.
33	Design and evaluation of microsphere drug delivery system for depot injection of anti psychotic drug.
34	Formulation development studies on solid oral dosage form for genneric molecule.
35	Formulation and evaluation of solid oral delivery system of a model anti retroviral agent.
36	Design and evaluation of extended release floating microballoons for better management of hypertension.
37	STUDIES ON DESIGN AND DEVELOPMENT OF TABLET DOSAGE FORMS WITH SPECIAL EMPHASIS ON GENERIC USE.
38	Design and evaluation of azt-loaded controlled release suppository for vaginal and rectal use.
39	Studies on lyophilization of injectable formulations containing model synthetic nucleoside analogs.
40	Design and evaluation of controlled release nanoparticulate drug delivery system of nsaids.
41	Similarity factors in dissolution profiling of uncoated and gelatin enrobed tablets.
42	Formulation, design and evaluation of solid oral unit dosage formsfor generic market.
43	Preparation and evaluation of sustained release matrix tablets of aceclofenac.

Pharmaceutical Technology Projects

Sr.No	Dissertation title
01	Formulation and evaluation studies on controlled drug delivery system of solid oral dosage form
02	Formulation and evaluation of colon specific targeted drug delivery system for the management of crohn's disease
03	Formulation development studies on extended release drug delivery system for management of cardiovascular disorders
04	Design and evaluation of extended release drug delivery system containing antidiabetic drug
05	Design and evaluation of controlled release lipospheric drug delivery system of an anti-diabetic drug
06	Formulation and evaluation of fast dissolving tablet of a model antidiabetic drug
07	Solubility enhancement of a model biopharmaceutics classification system-ii drug using liquisolid compacts
08	Formulation and evaluation of solid lipid nanoparticles containing griseofulvin
09	Formulation and evaluation of nanosuspension containing erythromycin
10	Design and evaluation of sustained release dosage form of an antidiabetic drug
11	Formulation and evaluation of controlled release ocular inserts
12	Formulation and evaluation of multivitamin soft gelatin capsules and its process optimization
13	Formulation and evaluation of gastro retentive drug delivery systems
14	Formulation and evaluation of fast release capsules of an anti-diabetic drug using semi solid matrix filling technique
15	Development and physicochemical characterization of poloxamer solid dispersions of poorly soluble drug

Pharmaceutical Chemistry Projects

Sr.No	Dissertation title
01	synthesis and characterization of certain impurities present in clobazam bulk drug and study their impurity profile by hplc
02	synthesis and characterization of certain impurities present in propiverine, pargeverine and opipramol bulk drugs
03	synthesis and characterization of 5h dibenzo [a, d] cycloheptene derivative impurities present in amitriptyline, protriptyline, cyproheptadine and cyclobenzaprine bulk drugs
04	Synthesis and characterization of structurally similar compounds of cinnarazine, orphenhedrine citrate and doxylamine
05	Synthesis, characterization and hplc analysis of related substances of nitrazepam.
06	Synthesis and evaluation of central nervous system depressant activity of some indolizine derivatives
07	Synthesis and antimicrobial activity of sulphonamidoindolizines
08	some novel methods of synthesis of structurally related compounds of zotepine
09	synthesis and antimicrobial evaluation of benzimidazolo thiadiazoles and benzimidazolo triazoles
10	synthesis and characterization of structurally related compounds of clomipramine, trimipramine and loperamide
11	FSynthesis and antimicrobial evaluation of benzoxazino thiazolidinones and benzoxazino azetidinones
12	Synthesis and Antihypertensive Activity of Benzopyran derivatives
13	Antihypertensive Activity of Substituted Benzopyran Derivatives
14	Isolation of Major Chemical Constituents from Leaves of Azadirachta Indica towards Achieving Standardisation.
15	Synthesis of certain structurally related compounds of Alprazolam
16	Synthesis and Evaluation Of Structurally Related Compounds of Ritodrine
17	Isolation of Major Chemical Constituents from Fruits of Terminalia Bellirica towards Achieving Standardisation.
18	Synthesis of Impurities in the manufacture of Loprazolam and study of impurity profile by HPLC
19	Synthesis , Hydrolysis kinetics and comparative Anti-tubercular Activity of Indolizine Derivatives of Isoniazid/Pyrazinamide/Para-amino salicylic acid
20	Identification /Isolation, Estimation and Biological Evaluation of Phenols/Phenolic Acids of Rhizophora mucronata Bark
21	Synthesis, Characterization And HPLC analysis of Structurally related compounds of tetrazepam
22	Synthesis and Anti-Inflammatory Activity of Bezimidazolo Coumarins
23	Synthesis, Characterization of Structurally related compounds of Lorazepam and Temazepam
24	Zisomer control in synthesis of Flupentinol related Compound
25	Synthesis and characterization of Various Polymorphic forms of olanzapine
26	Synthesis and Anti-tubercular Activity of Indolizine Derivatives of Chalcones
27	Isolation and characterization of Chemical Constituents From Aerial Parts of Cardiospermum Halicacabum
28	Isolation and characterisation of Chemical constituents of Coccina Indica
29	Isolation and characterization of Chemical constituents of Areial part extract Lanata
30	Isolation and characterization of Chemical constituents of Bauhinia Variegata leaf extract
31	Isolation and characterization of Chemical constituents of Achyranthes Aspera Extract
32	Synthesis and Antimicrobial, Anti-inflammatory Activity of Some Benzofuran Derivatives
33	Synthesis of Impurities in the manufacture of Carbamazepine and Oxcarbamazepine
34	Synthesis and characterization of new Para-fluro Substituted phenyl compounds
35	Isolation of Chemical Constituents from Aerial Parts and Roots of Boerhaavia Diffusa for achieving Standardisation

Pharmacology Projects

Sr.No	Dissertation title
01	Effect of different statins (hmg-coa reductase inhibitors) on gastric and duodenal ulcers in rat
02	Pharmacodynamic interaction study of momordica charantia with rosiglitazone
03	Pharmacological evaluation of extracts of allium sativum linn bud for antifertility activity in female rats
04	Effect of different calcium channel blockers (voltage gated-l, p, t types) on gastric and duodenal ulcers
05	Effects of methanolic extract of momordica charantia fruits on gastric and duodenal ulcers
06	Evaluation of the crocin, a constituent of crocus sativus (saffron) for immunomodulatory activity
07	Evaluation of acacia catechu for immunomodulatory activity
08	Comparative study of the hepatoprotective efficacy of a few marketed polyherbal products
09	Effect of central administration of losartan, an angiotensin-ii receptor antagonist on gastric and duodenal ulcers
10	Evaluation of wound healing activity of sesamum indicum l seeds and oil in rats
11	Evaluation of the methanolic extract of morus alba linn. leaves (mulberry) for immunomodulatory activity
12	Cardioprotective studies of hydroalcoholic extract of sida cordifolia l. leaves in rats
13	Effect of central administration of ondansetron, a 5-ht3 receptor antagonist on gastric and duodenal ulcers
14	Effect of cod liver oil on gastric and duodenal ulcers
15	Effect of allium sativum linn. bulb juice on gastric and duodenal ulcers
16	Effect of central administration of losartan, an angiotensin-ii receptor antagonist on gastric and duodenal ulcers
17	Evaluation of methanolic extract ofanisochilus carnosus leaves for antiulcer activity
18	Evaluation of crocin, a constituent of crocus sativus (saffron) for immunomodulatory activity
19	Evaluation of wound healing activity of bauhinia purpurea leaf extracts in rats
20	Evaluation of antinociceptive effect of terminalia bellirica fruit extracts in diabetic peripheral neuropathic rat models
21	Evaluation of human urine for wound healing activity in rats
22	Pharmacological evaluation of hydroalcoholic extract of tylophora indica for cardioprotective activity in rats
23	Evaluation of the methanolic extract of morus alba linn. leaves (mulberry) for immunomodulatory activity
24	Evaluation of wound healing activity of sesamum indicum l seeds and oil in rats
25	Hepatoprotective studies of Zizyphus jujube fruit extract in Rat.
26	Evaluation of Mimosa pudica root extract for wound healing activity in animal
27	Comparative studies of hepatoprotective efficacy of few plants
28	Pharmacodynamic interaction of momordica charantia with preparation in diabetic complication
29	Evaluation of antinociceptive effect of Withania somnifera (Ashwagandha) root extractin diabetic pheripheral neuropathic model of rat.
30	Evaluation of antinociceptive effect of Terminlau aBellirica fruit extract in diabetic peripheral neuropathic rat models.
31	Evaluation of the Crocin. A constituent of crocus sativus (Saffron) for immunomodulation activity
32	Evaluation of wound healing activity of Bauhinia purpurea leaf extract in rats
33	Evaluation of methanolic extract of Anisochius canosus leaves for antiulcer activity
34	Evaluation of the methanolic extract of Moringa olefera Lam leaves (Drumstick) for immunomodulatory activity
35	Pharmacological evaluation of various fraction of methanolic extract of Terminalia bellirica Roxb fruit in diabetic neuropathic rats
36	Pharmacological evaluation of various fractions of aqueous extract of Terminalia bellirica Roxb fruit in diabetic neuropathic rats
37	Pharmacological evaluation of leaves extract of ocimum sanctum in diabetic neuropathic rats
38	PPharmacological evaluation of Allium sativum Linn (Bulb Juice ) in diabetic neuropathic rats
39	Pharmacological evaluation of methanolic extract of Momordica charantia linn in diabetic neuropathic rats
40	Effect of Serencarpus anacardioum fruit extract on myocardial potency of Propranalol an interactive study
41	Pharmacodynamic interaction of Phyllanthus reticulatus leaves extract with Propranolol during myocardial damage
42	Evaluation of rejuvenative activity of Aegle marmelos extract in animals
43	Herb drug interaction. An animal study on effect of Aegle marmelos leaves extract in presence of Propranolol
44	Study of immunomodulation activity of Aegle marmalus leaf extract in animal
45	Interaction of Carrot (Daucus carota) with Pantoprazole and ranitidine for antiulcer activity in animals
46	Pharmacodynamic interaction of leaves ( Citrus Limon) with conventional antiulcers against experimentally induced ulcers in rats.
47	Cardioprotective interaction of Allium sativum with enalapril in Isoproterenol induced myocardical damage in rats
48	Evaluation of Hepatoprotetcive and Anti-inflammatory activity of Aqueous leaf extract of Blumea mollin in Rats
49	Pharmacodynamic interaction of Fenugreek seed extract with Fluvastatin in diabetes induced vascular dysfunction
50	Pharmacokinetic interaction between Allium sativum (Garlic) with few cardioprotective drugs
51	Studies on Pharmacodynamic interaction of Garlic and Metoprolol in rats with myocardial dysfunction and metabolic derangements
52	The potency of Garlic in presence of repaglinide and Amlodipine during ischemia-reperfusion induced myocardial injury in diabetic rats
53	PPotency Evaluation of combined therapy of Losartan and Garlic during isoprenaline mediated cardiac dysfunction in rats
54	Interaction of garlic and its constituents, S-alllyl cystein with Atenolol in Isoproterenol induced myocardial injury in rats
55	Pharmacodynamic interaction of Allium sativum with Captopril and Metformin with diabetes and myocardial dysfunction
56	Combined effect of Trigonella Foenum Graecum seed extract with oral hypoglycemics in diabetic neuropathic pain
57	Pharmacodynamic interaction of polyphenolic rich extract of Fenugreek seeds with oral hypoglycemic agents in diabetic induced gastropathy
58	The potential for interaction of Garlic and S-Allyl cysteine with carvedilol during isoprenaline mediated myocardial necrosis in rats
59	The Potential for interaction of Gliclazide and Ramipril with Garlic during myocardial damage in diabetic rats
60	Interactive study of Trigonella Foenum Graecum seed extract with oral hypoglycemic agents in diabetic induced nephropathy
61	Anti-obesty screening of Figs (Ficus carica) in animals fed on Atherogenic and cafeteria diet
62	Combined effect of Quercetin with oral hypoglycemics in diabetes induced increase in Susceptibility to ulerogenic stimuli
63	PPharmacological evaluation of Momordica charantia fruit extract in diabetic induced nephropathy
64	Pharmacological evaluation of Trigonella Foenum Graceum seed extract in diabetes induced increase in susceptibility to ulcerogenic stimuli
65	Graceum seed extract in diabetes induced increase in susceptibility to ulcerogenic stimuli
66	Evaluation of Anti-Obesity Potential of Cashew Nut (Anacardium Occidentale) in Animals
67	Combined effect of Quercetin with Oral hypoglycemics in diabetic neuropathic pain
68	Pharmacodynamic interaction of Syzygium cumuni seed kernel extract with oral hypoglycemics in diabetic neuropathic pain
69	Evaluation of Anti-Obesity Potential of Almomd (Prunus dulcis) in animals
70	Cardioprotective potential of Cahsew nut in Isoproterenol induced myocardial damage in rats
71	Evaluation of Antihyperlipidemic activity of Stem bark extract of Erythrina variegata in hyperlipidemic rat model.
72	Cardioprotective Potential of Fig (Ficus carica) in Isoproterenol induced myocardial damage in rats
73	Evaluation of Anti-inflammatory and NAlgesic activity of Pinus Roxburghii leaves extract
74	Drug-Drug interaction studies of carvedilol with Pioglitazone in diabetic rats
75	Combined effect of Syzygium cumini seed kernel extract with oral hypoglycemics in Type II diabetic induced nephropathy
76	Cardioprotetcive interaction of cucumis Melo with enalapril in isoproterenol induced myocardial damage in rats
77	Cardioprotetcive interaction of cucumis Melo with enalapril in isoproterenol induced myocardial damage in rats
78	Pharmacodynamic interaction of Ocimum sanctum leaves extract with oral hypoglycemic agents in diabetes induced Gastropathy
79	Combined effect of Syzygium cumini seed kernel extract with oral hypoglycemic s in diabetic induced increase in susceptibility to ulcerogenic stimuli
80	Interactive study of Quercetin with Oral hypoglycemic agents in Diabetes induced Nephropathy
81	Interactive study of Emblica officinalis Gaertn Fruit extract with Oral hypoglycemics in diabetes induced nephropathy
82	Pharmacodynamic interaction of Aloevera with pantoprazole against experimentally induced ulcers in rats
83	Combined effect of Emblica Officinalis fruit extract with oral hypoglycemics in diabetic neuropathic pain
84	IEvaluation of Antithrombocytopenic potential of Amla and kiwi fruit juices in animals.
85	Combined effect of Emblica officinalis fruit extract with oral hypoglycemics in diabetes induced increase in susceptibility to ulcerogenic stimuli
86	Potential benefits of papaya leaves and Grape fruit juices for management of thrombocytopenia
87	Comparative bioavailability and bioequivalence of the formulations of Benzimidazoles-oral antiulcer drugs
88	Combined effect of Momordica charantia fruit extract with oral hypoglycemics in diabetic neuropathic pain
89	Pharmacological evaluation of ethanolic extract of Dalbergia sissoo for its antidiabetic activity
90	Pharmacodynamic interaction of Momordica charantia with oral hypoglycemic agents in diabetes induced gastropathy

Quality Assurance Projects

Sr.No	Dissertation title
01	Cleaning Validation in Manufacturing unit for Solid Oral Dosage Forms
02	Process Validation of Herbal Tablet Dosage Form
03	Process Validation of an Active Pharmaceutical Ingredient Used in Gastrointestinal Disorder
04	Study of risk Analysis as an element of Process Validation of a Solid Unit Dosage form
05	Study of Critical Quality Attributes of a Solid Dosage Form
06	Stability Indicating Process Validation of an Anti Ulcer Drug in Solid Dosage Form
07	Process Validation of an Active Pharmaceutical Ingredient Used in cardiac care
08	Method developent and validation of Statins in Pharmaceutial Dosage forms Using HPLC
09	Process Validation of an Anti Diabetic Active Pharmaceutical Ingredient
10	Study of Concurrent Process Validation of an Antibiotic Solid Dosage Form
11	Cleaning Validation Of Equipments Used In Manufacturing Unit Of Oral Soild Dosaage Forms
12	Method Development And Validation Of Estimation Of Ursolic Acid In Tulsi By HPLC Technique
13	Process Validation Of Oral Solid Dosage Forms Of Cephalosporins
14	Equipment Validation Of Lyophilizers And Autocalves In Manufacturing Of Sterile Pharmaceuticals
15	Process And Cleaning Validation Of Sterrile Injectables Of Antibiotics
16	Method Development And Validation For Estimation Of Rosmarnic Acid Extract By HPLC Technique
17	Process Validation Of Solid Dosage From Of Proton Pump Inhibitor
18	Development And Validation Of An Analytical Method For The Determination Of Oseltamivir By Lc-Ms Technique
19	Development And Validation Of Stability Indicating Assay Method For Ranitidine Hydrochloride
20	Process Validation Of Proton Pump Inhibitor In Oral Solid Dosage Form

Pharmaceutical Analysis Projects

Sr.No	Dissertation title
01	Method development and validation of determination of impurities in Deferastox
02	Method development and validation for simultaneous estimation of Tenofovir-Lamuvudine by using HPLC
03	Analytical method development and validation of Irbesartan,hypertensive drug
04	Method development and validation of Febuxostat tablets
05	Method development and validation for analysis of impurities and related substances in Statins using HPLC
06	Analytical method development and validation for the estimationf of Nevirapine byLC-MS in human plasma
07	Method development and validation for analysis of impurities related substances in the biological Insulin analogues using HPLC
08	Analytical method development for Coccinia indica extract by RP-HPLC method
09	Spectrophotometric and HPLC method development of simultaneous estimation of anti tubercular drugs.
10	Method development and validation of determination of impurities and related substances in Immunosuppresants by using HPLC
11	Method development and analysis of anti-diabetic drugs by using HPLC
12	Method development and validation for the analysis of Risedronate sodium and Calcium carbonate using RP-HPLC technique in pharmaceutical dosage forms
13	Method development and validation for simultaneous estimation of Tamsulosin hydrochloride-Finasteride
14	Analytical method development and validation of anti tubercular drugs using HPLC.
15	Method development and validation for the analysis of anti hyper tensive drugs using HPLC
16	Prosses validation of liquid dosage forms Dexteromethorphan-Chlorpheniramine maleate.
17	Analytical method validation of related substance of pemetrexed injection
18	Degradation study of Irbesartan and analysis of its fragments

Ph. D Projects

Phytochemical analysis and pharmacological screening of tectona grandis leaves for wound healing activity
nayeema,
guide : prof md karvekar, rajiv gandhi university of health sciences,karnataka

Synthesis of benzofuran deravatives their microbiological and pharmacological evaluation
r.Harish,
guide : dr m. D.Karvekar, rajiv gandhi university of health sciences,karnataka

Ssynthesis, hydrolysis kinetic and biological evalution of some antihypertensive co-drugs
mayukh baidya,
Guide : DR Amit Kumar Das , Rajiv Gandhi University Of Health Sciences,karnataka

Sphytochemical and biological evalution pytochemical of rhizophora mucronata bark,
Rohini RM,
Guide : DR Amit Kumar Das , Rajiv Gandhi University Of Health Sciences,karnataka

Sanalysis and pharmacological screening of psidiumguajava linnleaves for its hepatopr otective acgtivity,
Chanchal Roy,
Guide : DR Amit Kumar Das , Rajiv Gandhi University Of Health Sciences,karnataka

Design and evaluation of novel topical intravaginal formulations of microbicidal agent for prophylaxis of hiv and other venereal diseases,
Arshad Bashir Khan
GUIDE : Dr.R.S.Thaku

Design, in silico prediction, synthesis and pharmacological evaluation of various novel analogues derived from piperine,
Sakshi Baradwaj
GUIDE : Dr. Sonal Dubey Sharma

Formulation and evaluation of antibiotic loaded liposomal inhalations for pulmonary infections,
Mrs. Sayani Bhattacharya

Design and evaluation of nano lipid carrier loaded transdermal patches of oral antidiabetic drug,
Mrs. Ashwini